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Audiovisuals with series with editor Language for Books and Other Individual Titles in Audiovisual Formats (required) General Rules for Language • Give the language of publication if not English • Capitalize the language name • Follow the language name with a period Books and Other Individual Titles in Audiovisual Formats 939 Specific Rules for Language • Audiovisuals appearing in more than one language Box 52 generic atorvastatin 40 mg fast delivery. Paranormale heilmethoden auf den Philippinen = Paranormal healing in the Philippines [videocassette] order atorvastatin 10 mg online. Audiovisuals published with text in multiple languages Notes for Books and Other Individual Titles in Audiovisual Formats (optional) General Rules for Notes • Notes is a collective term for any type of useful information given afer the citation itself • Complete sentences are not required • Be brief Specific Rules for Notes • Audiovisual accompanied by a booklet or other material • Other types of material to include in notes Box 53. Te notes element may be used to provide any information the compiler of the reference feels is useful to the reader. Examples of notes are: • If the audiovisual was sponsored by or prepared for a particular organization, give the name Fluoride: the magnifcent mineral [motion picture]. Health and the built environment: the efects of where we live, work and play [videocassette]. Audiovisuals with supplemental note included Examples of Citations to Books and Other Individual Titles in Audiovisual Formats 1. Nuclear cardiac imaging: equilibrium and gated frst pass radionuclide angiocardiography [videodisc]. Health and the built environment: the efects of where we live, work and play [videocassette]. April and Renee: the supermodel, the tennis player, and the discourses of trans/sexual diference [videocassette]. Audiovisuals with organization as author with subsidiary part of organization named Kaiser Permanente, Southern California Permanente Medical Group. Udalenie doli legkogo pri tuberkuleze [Lung lobe resection in tuberculosis] [motion picture]. Audiovisuals with more than one organization as author American Association of Oral and Maxillofacial Surgeons; American Academy of Oral Pathology. Audiovisuals with no authors found Collaborative research with communities: value added & challenges faced [videocassette]. New York: Society for French American Cultural Services and Educational Aid; 1991. New York: Society for French American Cultural Services and Educational Aid; 1991. Udalenie doli legkogo pri tuberkuleze [Lung lobe resection in tuberculosis] [motion picture]. Audiovisuals published with parallel text in two languages Choropampa: the price of gold = Choropampa: el precio del oro [videocassette]. Paranormale heilmethoden auf den Philippinen = Paranormal healing in the Philippines [videocassette]. Audiovisuals published with text in multiple languages A plastic story: a history of plastic surgery [videocassette]. Audiovisuals with Greek letters in titles β-arrestins: trafc cops of cell signaling [videocassette]. Audiovisuals with more than one type of medium Microhemagglutination assay methods in the diagnosis of syphilis [audiocassette + slide]. Case studies in human growth and development: a fexible instructional module [audiocassette + videocassette]. Following Antigone: forensic anthropology and human rights investigations [videocassette]. Optimizing the mammographic study: positioning and technical considerations [videodisc]. Audiovisuals with authors and producer(s), editor(s), or other secondary authors Hable M. Washington State University College of Nursing, Learning Resources Center, producer. Surgical techniques in orthopaedics: anterior cruciate ligament reconstruction [videodisc]. Kontrastdarstellung des Herzens und der grossen Gefasse im Rontgen-Kinoflm [Demonstration of the heart and large vessels in cine-radiographic flm] [motion picture]. Audiovisuals with place of publication inferred Fluoride: the magnifcent mineral [motion picture]. Health and the built environment: the efects of where we live, work and play [videocassette]. Audiovisuals with government agency as publisher Epidemiology and prevention of viral hepatitis A, B, C, D, E: an overview [slide]. Aspirin in the secondary and primary prevention of cardiovascular disease [audiocassette]. Audiovisuals with no publisher found Kontrastdarstellung des Herzens und der grossen Gefasse im Rontgen-Kinoflm [Demonstration of the heart and large vessels in cine-radiographic flm] [motion picture]. Books and Other Individual Titles in Audiovisual Formats 951 Bonn (Germany): [publisher unknown]; 1959. Audiovisuals with no place of publication or publisher found Onepauur ydarehur dephmpudhou kucmbi cpedocmehur [Ablation of a cyst in the mediastinum] [motion picture].

Titles of papers containing a Greek letter order 20mg atorvastatin amex, chemical formula generic atorvastatin 10mg mastercard, or another special character. Proceedings of the 9th International Workshop on Cardiac Arrhythmias; 2005 Oct 2-5; Venice. Paper from a proceedings in two equal languages Article Type for Conference Papers (optional) General Rules for Article Type • An article type alerts the user that the reference is to an abstract of a paper, not to the full paper • Place [abstract] afer the title of the paper • Follow the bracketed article type with a period Conference Publications 365 Specific Rules for Article Type • Titles of papers ending in punctuation other than a period • Titles of papers not in English Box 76. In: • If a translated title ends in another form of punctuation, such as a question mark or an exclamation point, keep that punctuation. Place (abstract) within the square brackets and end title information with a period. Etude de la permeabilite nasale dans les fentes unilaterales operees [Study of nasal permeability in patients with operated unilateral clefs] [abstract]. Abstract of a paper 366 Citing Medicine Connective Phrase for Conference Papers (required) General Rule for Connective Phrase • Use the word "In" followed by a colon and a space to connect information about the paper with information on the conference proceedings Conference Proceedings for Conference Papers (required) • Follow the instructions in Chapter 3A to enter proceedings citation information Location (Pagination) for Conference Papers (required) General Rules for Location (Pagination) • Give the inclusive page numbers on which the paper appears • Do not repeat page numbers unless they are followed by a letter. Follow it by a semicolon and a space, then the name of the additional material and its pagination. Paper with letters included in page numbers Language for Conference Papers (required) General Rules for Language • Give the language of publication of the paper if not English • Follow the language name with a period Example Entries for Language 9. If a paper has such supplemental material accompanying it, begin by citing the paper and the proceedings in which it is found. Proceedings of the 3rd International Conference on Gastroenterology Surgery; 2004 May 3-5; Bonn, Germany. Te potential role of macrophage migration inhibitory factor in migration of vascular smooth muscle cells [abstract]. Proceedings of the 1st International Conference on Polyphenols and Health; 2004 Nov 18-21; Vichy, France. Paper also printed as a part of a journal Examples of Citations to Conference Papers 1. Development, dynamics, and pathology of neuronal networks: from molecules to functional circuits. Proceedings of the 23rd International Summer School of Brain Research; 2003 Aug 25-29; Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands. Developing electronic patient records: employing interactive methods to ensure patient involvement. Proceedings of the Joint Conference of the Society for Economic Botany and the International Society for Ethnopharmacology; 1996 Jul 1-6; London. Biodiversity & health: focusing research to policy = Biodiversite & sante: de la recherche aux politiques. In: Colloque Energie Solaire et Sante dans les Pays en Developpement = Conference on Solar Energy and Health Care in Developing Countries; 1991 Nov 4-7; Paris. Proceedings of the 9th International Workshop on Cardiac Arrhythmias; 2005 Oct 2-5; Venice. Biodiversity & health: focusing research to policy = Biodiversite & sante: de la recherche aux politiques. Foot- and-mouth disease in the Americas: epidemiology and ecologic changes afecting distribution. Development, dynamics, and pathology of neuronal networks: from molecules to functional circuits. Proceedings of the 23rd International Summer School of Brain Research; 2003 Aug 25-29; Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands. Paper with title containing a chemical formula or special character 6 Sperling P, Lee M, Girke T, Zahringer U, Stymne S, Heinz E. A bifunctional Delta(6)- acetylenase/desaturase from the moss Ceratodon purpureus. Simultaneous, worldwide development strategies: implementation of global clinical trials and introduction of new sciences and technologies. Te 3rd Kitasato University-Harvard School of Public Health Symposium; 2002 Oct 2-3; Tokyo, Japan. Paper from a proceedings in a language other than English, with translation Boetsch G. La cura delle malattie: itinerari storici [Treating illnesses: historical routes]. Simultaneous, worldwide development strategies: implementation of global clinical trials and introduction of new sciences and technologies. Te 3rd Kitasato University-Harvard School of Public Health Symposium; 2002 Oct 2-3; Tokyo, Japan. Razvoj strokovnega jezika in dileme danasnjega dne [Developing professional language and current dilemmas]. La sante par les probiotiques: perspectives biofonctionnelles = Probiotics and health: biofunctional perspectives.

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Manuscript collection with physical description Availability for Manuscript Collections (required) General Rules for Availability • Enter the phrase "Located at" followed by a colon and a space • Give the name of the library or archive order 20mg atorvastatin amex, preceded by any subsidiary division(s) purchase atorvastatin 10 mg mastercard, and followed by a comma and a space. Bibliotyeka, Rossiiskaia Akademiia Meditsinskikh Nauk [Library, Russian Academy of Medical Sciences] or [Library, Russian Academy of Medical Sciences] • Translate names of organizations in character-based languages such as Chinese and Japanese. Tis rule ignores some conventions used in non-English languages to simplify rules for English-language publications. If you choose an angelicized form for a city name or choose a country code, use that same form or code throughout all references. Manuscript collection with availability Language for Manuscript Collections (required) General Rules for Language • Give the language of the collection if not English • Capitalize the language name • Follow the language name with a period Specific Rules for Language • Collections with items in more than one language Box 62. Manuscript collection with items not in English Notes for Manuscript Collections (optional) General Rules for Notes • Notes is a collective term for any type of useful information given afer the citation itself • Complete sentences are not required • Be brief Specific Rules for Notes • Collection accompanied by material in another medium • Collection with restrictions on use • Other types of material to include in notes Box 65. Gertrude Henle required to quote, cite, paraphrase, or publish any of the unpublished material during her lifetime. Notes is a collective term for any type of useful information given afer the citation itself. Examples include: • Explanatory information on the content of the collection Bailey, Zachariah. Board meeting notes, drafs of by-laws and constitutions, reports, correspondence, conference packets, and publications represent materials collected by Hinman during his executive involvement with the activities of six interrelated medical informatics societies. Manuscript collection with other notes Examples of Citations to Manuscript Collections 1. Manuscript collection standard citation with full name for authors Calderwood, Howard Black. Manuscript collection with organization as author Association of Military Surgeons of the United States. Manuscript collection with no author or compiler Collection concerning health resorts. Manuscript collection title not in English Fonds du Conseil de Recherches Medicales. McFarland collection in aerospace medicine and human factors engineering [microfche]. McFarland collection in aerospace medicine and human factors engineering [microfche]. Manuscripts and Preprints 887 Fonds du Conseil de Recherches Medicales [Collections of the Medical Research Council]. McFarland collection in aerospace medicine and human factors engineering [microfche]. Manuscript collection accompanied by material in another medium American College of Cardiology. Gertrude Henle is required to quote, cite, paraphrase, or publish any of the unpublished material during her lifetime. Proceedings of the History of Ophthalmology conferences held at the National Library of Medicine in March of 1988 and 1989. Introduction and Examples Preprints are complete and public drafs of scientifc documents, not yet certifed by peer review. Tese documents ensure that the fndings of the research community are widely disseminated, priorities of discoveries are established and they invite feedback and discussion to help improve the work. Te document was reviewed by colleagues before or in lieu of submitting to a publisher. Preprints, once the sole domain of the hard sciences, such as physics, are now found in the applied sciences, social sciences, business, and the arts and humanities. Since the majority or preprints originate and remain online, they are also called e-prints. Near optimal neural network estimator for spectral x-ray photon counting data with pileup. Books and Other Individual Titles in Audiovisual Formats Created: October 10, 2007; Updated: August 11, 2015. An audiovisual may be published in monograph form, such as a book on videodisc, or in journal form, distributed on videocassette or audiocassette. Cite audiovisuals using the standard format for journals and books (see Chapter 1 and Chapter 2), but add a type of medium afer the title to alert the user that special equipment is needed to view the publication. Te extent or length of an audiovisual is an optional component of a reference that may provide useful information to the reader. Provide extent as the total number of physical pieces, such as 387 slides or 1 videocassette.

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With respect to curve fitting generic atorvastatin 10mg with visa, a good model should be insensitive to minor random fluctuations (robust) but extremely sensitive to gross or systematic errors when they become accidentally included order 5mg atorvastatin. By computer simulation, a set of raw counts for the standard curve of an absolutely ideal assay as well as of two “unknowns” (“intermediate standards”) that had a logit-response of exactly + 1. Only B0-counts were arteficially increased (В); (C) shows the concomitant improvement o f fit in terms o f coefficient of correlation and Syx. The opposite to this situation is the occurrence of gross errors, of an “outlier” in between otherwise ideal points. Since, under routine conditions accuracy is not so easy to assess, one has to rely primarily on goodness-of-fit. A: the ideal assay; B: the “real” assay with minor random fluctuation o f standard points; C: the assay with a gross error (“outlier’’) in between accurate points; D: the assay with a gross systematic error in standards. No model should claim to be superior to another model until comparisons have been made under otherwise identical conditions —same data, same criteria”. Thus, the total variation in the interpolated analyte concentration of an unknown sample determined in replicates is —besides the experimental replicate scatter —an additional variable of the position on the standard curve; hence its analyte content. The weight to be assigned to a logit-value is reciprocal to a smooth predicted variance function. The logit-log model is a special case for such general considerations as to heteroscedasticity. A theoretical variance profile obtained from a relation given by Rodbard is shown in Fig. Hence, for curve fitting, a weight that corresponds to the reciprocal of the variance at the respective inhibition (B/B0) level will have to be assigned to each observation of response. Accordingly, points in the middle of the range get the greatest weight (100%), while those approaching the end-points (extremes) are weighted less or receive even zero-weight. The “express route” is depicted by the thick lines and, strictly speaking, is applicable only for the ideal assay. Any deviations from this behaviour, however, call for weighting, for a “roundabout route”. Two principal approaches are in principle feasible: on the basis of observation, and on the basis of prediction. Strategy o f calibration curve calculation, plotting, inspection, weighting and fitting. If there are standards outside this range, accept them if they fit and reject them if they don’t. Owing to the central location, it is certainly on a sound statistical basis that the working range becomes thereby not at all diminished. If, however, it occurs somewhere at the extremes, rejection must obviously become associated with truncation of the analytical working range. The far more complex approach, both with respect to the mathematical- statistical procedures involved and with respect to the philosophical implications as to their particular justification behind it, is weighting on the basis o f prediction. Rodbard’s smooth function [B/B0(1 -B /B 0)B0]2 w eight=— r r i — Í--------- r to Draw J A0 = Î ; J = generally 1. The sophistication in data processing can be even further increased by iterative adjusting procedures during the curve-fitting process. Which is generally the best and what are the specific conditions that make a particular method break down? Relationship between B/B0 and logit B/B0 ( x -----x); relationship between L (or standards l-32U /tube, S1-S6) and logit В/В0 ( • ------• ); relationship between 2. It has already been implied that, by sticking to these “natural confines” in assay design and expectation, and later in assay use, mathematical weighting would become dispensable, even in logit-log which is known to “blow up” at the extremes. In addition we have superimposed a theoretical precision profile that was generated by inter­ polating a set of unknowns of a constant error in the original response variable (raw counts) of exactly 2. The ideal assay in the left lower corner ( 1), the “real” assay with minor fluctuations of random nature in the centre of the lower row (15 and 16), and the worst assay with progressive gross (= systematic) error in the right lower corner (14). It is impossible to account for all the details that emerged in this study, only the principal points being given here. What clearly emerged from this study is the fact that goodness-of-fit and accuracy of calibration curves behave, in principle, independently. This implies that the routinely available parameters for goodness-of-fit do not necessarily allow a reliable prediction regarding the accuracy. One must remember that it is the accuracy which is required, goodness-of-fit is only a by-phenomenon of a precise but not necessarily accurate calibration curve. Hence, the criterion to be placed above the criteria of goodness-of-fit and accuracy is concordance between these two. This question stresses the importance of using a standardized procedure and of extracting as many parameters as possible for goodness-of-fit and accuracy. This clearly shows the importance of good documentation of these parameters, and the necessity to include as many parameters as possible in continuous statistical calculations.

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Sulfation is also used to detoxify some normal body chemicals and is the main way we eliminate steroid hormones (such as estrogen) and thyroid hormones so that they don’t build up to damaging levels cheap 20 mg atorvastatin free shipping. Since sulfation is the primary route for the elimination of neurotransmitters as well buy generic atorvastatin 20mg on-line, dysfunction in this system may contribute to the development of some nervous system disorders. For example, the diet needs to contain adequate amounts of methionine and cysteine. Another key nutrient is the trace mineral molybdenum, which is required for most of the enzymes involved in sulfur metabolism. To ensure that sulfation is working adequately, consume adequate amounts of sulfur-containing foods, such as whey protein, eggs, red peppers, garlic, onions, broccoli, and brussels sprouts. Conjugation of toxins with acetyl coenzyme A (acetyl-CoA) is the method by which the body eliminates sulfa drugs (antibiotics commonly used for urinary tract infections). This system appears to be especially sensitive to genetic variation, with those having a poor acetylation system being far more susceptible to sulfa drugs and other antibiotics. While not much is known about how t o directly improve activity of this system, it is known that acetylation is dependent on thiamine (vitamin B ), pantothenic acid (B ), and vitamin C. It also helps to detoxify aspirin, menthol, vanillin (synthetic vanilla), food additives such as benzoates, and some hormones. Glucuronidation appears to work well in most of us and doesn’t seem to require special attention, except for those with Gilbert’s syndrome—a relatively common syndrome characterized by a chronically elevated serum bilirubin level (1. Previously considered rare, this disorder is now known to affect as much as 5% of the general population. The condition is usually without symptoms, although some patients do complain about loss of appetite, malaise, and fatigue (typical symptoms of impaired liver function). The main way this condition is recognized is by a slight yellowish tinge to the skin and white of the eye due to inadequate metabolism of bilirubin, a breakdown product of hemoglobin. Eating these foods not only improves glucuronidation but also has been shown to protect us from chemical carcinogens. To ensure that glucuronidation is working properly, eat sulfur-rich foods (see above) and citrus fruit (but not grapefruit). Sulfoxidation is the process by which the sulfur-containing molecules in drugs (such as chlorpromazine, a tranquilizer) and foods (such as garlic) are metabolized. It is also the process by which the body eliminates sulfite food additives used to preserve foods and drugs. Various sulfites are widely used in potato salad (as a preservative), salad bars (to keep the vegetables looking fresh), dried fruits (sulfites keep dried apricots orange), and some drugs (such as those used for asthma). Normally, the enzyme sulfite oxidase metabolizes sulfites to safer sulfates, which are then excreted in the urine. Those with a poorly functioning sulfoxidation system have an increased ratio of sulfite to sulfate in their urine. When the sulfoxidation detoxification pathway isn’t working very well, people become sensitive to sulfur-containing drugs and foods containing sulfur or sulfite additives. This is especially important for asthmatics, who can react to these additives with life-threatening attacks. Jonathan Wright, one of the leading holistic medical doctors in the country, discovered several years ago that providing molybdenum to asthmatics with an elevated ratio of sulfites to sulfates in their urine resulted in a significant improvement in their condition. Although most nutrition textbooks believe molybdenum deficiency to be uncommon, an Austrian study of 1,750 patients found that 41. One illustration of this is the strong odor in the urine that some people experience after eating asparagus (the odor is a function of variability in liver detoxification). While this phenomenon is virtually unheard of in China, it is estimated that almost 100% of the French experience such an odor; about 50% of adults in the United States notice this effect). While sophisticated laboratory tests are necessary to prove that a specific liver detoxification system is dysfunctional, several signs and symptoms can give us a good idea of when the liver’s detoxification systems are not functioning well or are overloaded. In general, anytime you have a bad reaction to a drug or environmental toxin you can be pretty sure there is a detoxification problem. The table below lists symptoms that are directly tied to a particular dysfunction. However, when the excretion of bile is inhibited (a condition called cholestasis), toxins stay in the liver longer. Cholestasis has several causes, including obstruction of the bile ducts and impairment of bile flow within the liver. The most common cause of obstruction of the bile ducts is the presence of gallstones. Currently, it is conservatively estimated that 20 million people in the United States have gallstones. Nearly 20% of women over 40 and 8% of men over 40 are found to have gallstones on biopsy, and approximately 500,000 gallbladders are removed in the United States each year because of gallstones. The prevalence of gallstones in this country has been linked to the high-fat, low-fiber diet consumed by the majority of Americans.

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